(1R,2R)-(+)-1,2-Diphenyl-1,2-ethanediamine is an important chiral reagent with a C2-axis of symmetry.
It has been widely used in asymmetric synthesis and optical resolution, such as asymmetric epoxidation of unfunctionalized olefins, asymmetric aldol condensation, asymmetric Diels-Alder reaction, asymmetric allylation of carbonyl, Synthesis of optically active allenyl alcohols and propynyl alcohols, asymmetric epoxidation of olefins without functional groups, and resolution of binaphthol.
used as chiral solvation agent for determination of enantiomeric excess of chiral acids by NMR.
It is used in various catalyst systems for asymmetric reactions.
