Abacavir

Abacavir

CAS No 136470-78-5
Formula C14H18N6O
Application

Abacavir is an antiviral drug with anti-HIV effects

A nucleoside reverse transcriptase inhibitor (NRTI), like other nucleoside reverse transcriptase inhibitors, is an inactive prodrug that is converted in humans to the active metabolite triphosphate by cellular kinases Carbovir, an analog of deoxyguanosine triphosphate (dGTP), competes with the latter or integrates into viral DNA, inhibits the activity of HIV reverse transcriptase, and causes defects in the integrated nucleoside and makes the viral DNA Replication stopped.


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