Aminopterin

Aminopterin

CAS No 54-62-6
Formula C19H20N8O5
Application

A white to yellow powder; commonly used as the dihydrate which forms clustersof yellow needles;


Antineoplastic, antirheumatic, folic acid antagonist


Used in the production of anti- neurogranin antibodies.

A folic acid antagonist. Its actively transported into cells by thefolate transporter. In the cell, its converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, that, in turn, binds to dihydrofolate reductase and inhibits its activity.


LEAD OPTIMA ELEMENT TECH
Web:www.loptima.com                    E-mail: sales@loptima.com        Tel:(+86)18-423-717-818                                               
Add: No.5, Huoju Avenue, Jiulong High Tech Park (China Chongqing Pilot Free Trade Zone, Erlang area), CQ 400080 China