HPLC>98%
Treatment for Non-small cell lung cancer ,metastatic breast cancer ,refractory lymphoma, ovarian cancer, head and neck cancer;
Antimigraine, 5HT[1B/1D] agonist
Vinorelbine is a semisynthetic vinca alkaloid differing from vinblastine in the catharantine moiety of the molecule.
Clinically it has been found effective in the treatment of non-small cell lung cancer, advanced breast cancer, ovarian cancer and Hodgkins disease.
Side effects:
Although dose-limiting granulocytopenia is the major adverse effect, potentially fatal interstitial pulmonary changes have been noted, and patients with symptoms of respiratory distress should be promptly evaluated. As with all vinca alkaloids, elimination is primarily hepatobiliary, and dosage reduction should be considered in patients with liver dysfunction.
