5-Azacytidine

5-Azacytidine

CAS No 320-67-2
Formula C8H12N4O5
Application

White or almost white crystalline powder

Loss on drying ≤1.0%

Assay(HPLC) ≥98.0%


A potent growth inhibitor and cytotoxic agent. It acts as a demethylating agent by inhibiting DNA methyltransferase

Antineoplastic;'Antimetabolite

Antianginal

5-Azacytidine, its incorporation into RNA alters RNA synthesis and processing, and results in inhibition of protein synthesis. It has been used as a cancer chemotherapeutic agent. It is a powerful bacteriostatic, antitumor, and mutagenic agent; it also exhibits immunosuppressive, antimitotic, radioprotective, and virostatic effects.


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