Atazanavir

Atazanavir is an azapeptide HIV-1 protease inhibitor.

This product selectively inhibits the specific processing of viral Gag and Gag-Pol polyproteins in HIV-1 infected cells, thereby blocking the formation of mature virus.

In vitro antiviral activity: Atazanavir in the absence of human serum against a large number of laboratory and clinically isolated HIV-1 strains colonized with peripheral blood monocytes, macrophages, CEM-SS cells and MT2 cells The average 50% inhibitory concentration (IC50) of 2 to 5 nM.