Bicalutamide

Bicalutamide is a non-steroidal androgen antagonist that competes with androgens for androgen receptors, blocks the uptake of androgens by cells, and inhibits the binding of androgens to target organs. After binding, it forms receptor complexes, enters the nucleus, and binds to nucleoproteins, thereby inhibiting the growth of tumor cells; it can be used as a first-line drug for palliative treatment of advanced prostate cancer.